CyTOF® Instrument
Up to 100 independent detection channels
The unique multiplex analysis capability of the CyTOF® system is already enabling new insights into the functional complexity of biological systems at the single cell level. A recent example published in Science describes how the technology was used with an immunophenotyping panel of 31 labeled antibodies to provide a uniquely detailed view of cell differentiation in the human hematopoietic system.
The CyTOF® technology will potentially enable analysis of up to 100 stable isotope labels in a single sample. The mass cytometer provides at least 3 orders of magnitude resolution between adjacent metal isotopes eliminating the need for compensation. Since the sensitivity is practically the same across all metals measured, the selection of labels used in an experiment is arbitrary.
Reproducibility between samples, between systems
CyTOF® will deliver robust and reproducible performance from the first day of installation in your laboratory. Data generated is highly reproducible with a low coefficient of variation between replicates, between systems and between users. This characteristic makes its use particularly well suited to multi-site or longitudinal studies.
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Absolute quantification of target molecules
The CyTOF® instrument offers the specificity, dynamic range and quantitative capability of atomic mass spectrometry in a format that is familiar to flow cytometry practitioners. Mass cytometry offers a unique opportunity to simultaneously analyze more subtle quantitative changes in intracellular and membrane bound proteins within complex cell populations.
View quantification data.